The Desiya Murpokku Dravida Kazhagam (transl. National Progressive Dravidian Federation; abbr. DMDK) is an Indian regional political party in the state of Tamil Nadu. DMDK is a Dravidian party founded by Vijayakanth at Madurai on 14 September 2005. The party head office is in Koyambedu, Chennai.

This party contested all 234 seats in the state elections in May 2006 with Vijayakanth contesting Vridhachalam. The party polled almost 30 lakh votes (a total of about a 10% share). All the candidates of the DMDK, with the sole exception of Vijayakanth, lost the elections in 2006. In by-elections to Madurai Central assembly constituency, DMDK secured around 17,000 votes, which was 2,000 votes less than All India Anna Dravida Munnetra Kazhagam (AIADMK). DMDK secured many seats in Local Body elections. Vijaykanth and his party contested the 2009 Lok Sabha polls as an independent party in all 39 constituencies in the state, winning no seats. The party won 29 seats in the 2011 assembly election and became the official opposition party with Vijayakanth as the Opposition Leader.