Oxfordshire is a landlocked county in the far west of the government statistical region of South East England. The ceremonial county borders Warwickshire to the north-west, Northamptonshire to the north-east, Buckinghamshire to the east, Berkshire to the south, Wiltshire to the south-west and Gloucestershire to the west.

The county has major education and tourist industries, and is noted for concentrations of performance motorsport, car manufacturing and technology companies. Oxford University Press is the largest firm among a concentration of print and publishing firms; the University of Oxford is also linked to the concentration of local biotechnology companies.

As well as the city of Oxford, other centres of population are Banbury, Bicester, Kidlington and Chipping Norton to the north of Oxford; Carterton and Witney to the west; Thame and Chinnor to the east; and Abingdon-on-Thames, Wantage, Didcot, Wallingford and Henley-on-Thames to the south. All its zones south of the Thames: the Vale of White Horse and parts of South Oxfordshire were within the historic county of Berkshire, including the highest point, the 261-metre (856 ft) White Horse Hill.

Oxfordshire's county flower is the snake's-head fritillary.