| Institute for Contemporary Shamanic Studies | Academic & Science |
| Interactive Chemical Safety for Sustainability | Academic & Science |
| International Civil Society Support | Academic & Science |
| Innis College Student Society | Academic & Science |
| Intelligent Customer Support System | Business |
| I&C Systems Integrator & Service Company, Inc. | Business |
| Deutsche Telekom International Carrier Sales & Solutions | Business |
| Internal Compulsive Scout Syndrome | Community |
| Innovative Community Support Services | Community |
| Immanuel Christian Secondary School | Community |
| Integrated Control and Safety System | Computer Hardware |
| Internet Connection Secure Server | Computing |
| Intelligent Customer Support Systems | Computing |
| Iowa Cooperative Soil Survey | Earth Science |
| International College for Security Studies | Educational Institute |
| Integrated Control and Safety Systems | General |
| Instructional Classroom Support Services | General |
| Industrial Control System Security | General |
| Instrumentation Control and Safety Systems | General |
| Integrated Child's Safety Seat | General |
| Indiana Council for the Social Studies | Governmental |
| Iowa Council for the Social Studies | Governmental |
| International Commission for Salesian Studies | Governmental |
| Illinois Council for the Social Studies | Governmental |
| Institute for Complex System Simulations | Governmental |
| Institute for Complex Systems Simulation | Governmental |
| Illinois Council for the Social | Governmental |
| Institute for Complex Strategic Studies | Governmental |
| Institute for Cognitive Science Studies | Governmental |
| International Carrier Sales Solutions | International |
| International Customer Service Standard | International |
| International Cell Surgical Society | International |
| International Conference on Small Science | International |
| International Centre for Sport Security | International |
| International Climate Space Station | International |
| International Carotid Stenting Study | Medical |
| Intra-Cranial Self-Stimulation | Medical |
| Institute for Complex Scientific Software At Northeastern University | Softwares |
| Inn-client Server Systems | Softwares |
