The Spokan or Spokane people are a Native American Plateau tribe who inhabit the eastern portion of present-day Washington state and parts of northern Idaho in the United States of America.

The current Spokane Indian Reservation is located in northeastern Washington, centered at Wellpinit (Sčecuwe). The reservation is located almost entirely in Stevens County, but also includes two small parcels of land (totaling about 1.52 acres [0.62 ha]) in Lincoln County, including part of the Spokane River. In total, the reservation is about 615 square kilometres (237 sq mi).

The city of Spokane, Washington (Sʎˈetkʷ) is named after the tribe. It developed along the Spokane River, within the historic ancestral land of the tribe, but not within the reservation (see map).

The Spokane language (Npoqínišcn) belongs to the Interior Salishan language family, being a dialect of Montana Salish. Therefore they are close kin both by language and culture to the neighboring Bitterroot Salish (Flathead) (Tˈatˈʔayaqn) and Pend d'Oreilles. They were in loose alliance with other Plateau tribes - and sometimes the Kutenai (Sqlˈse), Crow Nation (Stemčiʔ) and Cree-Assiniboine (Iron Confederacy) (Ncoʕʷaqs) joined in - against their common enemy (Sˈmen), the mighty Blackfoot Confederacy (Sčqˈʷišni) and later Lakota people (Hułnʔixʷtˈusm) on the east. The precontact population of the Spokane people is estimated to be about 1,400 to 2,500 people. The populations of the tribe began to diminish after contact with settlers and traders due to mortality from new infectious diseases endemic among the Europeans, and to which the Spokane had no acquired immunity. By 1829 a Hudson Bay Company trader estimated there were about 700 Spokane people in the area. Since the early 20th century, their population has been steadily increasing: in 1985 tribal enrolled membership was reported as 1,961. In 2000 the US census reported the resident population of the reservation to be around 2,000 people.