The Pontifical Catholic University of Valparaiso (Spanish: Pontificia Universidad Católica de Valparaíso) (PUCV), also known as Universidad Católica de Valparaíso (UCV), is one of six Catholic universities in Chile and one of the two pontifical universities in the country, along with the Pontifical Catholic University of Chile. It is located in Valparaíso, Chile and has approximately 14,000 students.

PUCV attracts students from different areas of Chile, as well as hundreds of exchange students from Europe, North America and several countries from South America, due to its convenient student exchange programs. It is recognized as a traditional institution with high academic prestige and as a complex university due to its important research and educational development in the fields of science, engineering, humanities and arts. As a Catholic university, it answers directly to the Holy See and the Bishopric of Valparaíso. It is a private university with state support.

PUCV is an urban university. It has a central campus known as Casa Central (Central House) located in downtown Valparaíso, only a few blocks away from the Chilean Congress, the Metro, and the Pacific Ocean. One of the drawbacks of being an urban university is the difficulty of growing at the original site of its foundation. Several PUCV buildings are on the historic palm-tree-lined Avenida Brasil, but most of its schools are dispersed in throughout Valparaíso, Viña del Mar, Quilpué and Quillota.

It was positioned 29th at the QS Latin America University Ranking 2014 (5th nationwide). At the 2014 edition of the América Economía magazine university ranking, it was positioned 5th nationwide and first in the Region of Valparaiso.