The Baskin School of Engineering is the school of engineering at the University of California, Santa Cruz. It consists of six departments: Applied Mathematics, Biomolecular Engineering, Computational Media, Computer Science and Engineering, Electrical and Computer Engineering, and Statistics.

The school was formed in 1997 and endowed with a multimillion-dollar gift from retired local engineer and developer Jack Baskin.

Although it is a relatively young engineering school, it is already known in the Silicon Valley region and beyond for producing prominent tech innovators, including the founders of companies Pure Storage, Cloudflare, Concur Technologies, Five3 Genomics, and a host of other startups. It is a leader in the field of games and playable media, and was the first school in the country to offer a graduate degree in Serious Games. The school is also well-known for its research in genomics and bioinformatics, and played a critical role in the Human Genome Project. Researchers at UC Santa Cruz were responsible for creating the UCSC Genome Browser, which continues to be an important open-source tool for researchers in genomics.