| Instituto Cubano de Hidrografia | Academic & Science |
| Information Clearing House | Academic & Science |
| International Conference on Harmonisation (MedDRA) | Academic & Science |
| Integrity College of Health | Academic & Science |
| Impac Commercial Holdings, Inc. | Business |
| Investors Capital Holdings | Business |
| Institute of Child Heath | Community |
| International Conference on Harmonisation | Community |
| Intangible Cultural Heritage | Community |
| Institute for Constitutional History | Community |
| I/O Controller Hub | Computers |
| Input Output Controller Hub | Computing |
| Integrated Controller Hub | Computing |
| Intel Chipset | Computing |
| Indication Channel | Computing |
| Idea Chain Coin | Cryptocurrency |
| iCherry Finance | Cryptocurrency |
| Indigo Cat Hat | General |
| Intergalactic Crack Heads | General |
| In Center Hemodialysis | General |
| Intra Circle Hub | General |
| Inner-City Hustler | Governmental |
| Intelligent Corruption Handling | Governmental |
| International Conference on Harmonization (of Technical Requirements for Registration of Pharmaceuticals for Human Use) | Governmental |
| International Council For Homeopathy | Governmental |
| Institute of Child Health | Governmental |
| Interagency Council on Homelessness | Governmental |
| International Council on Harmonisation | Governmental |
| International Council for Harmonisation | International |
| International Convention on Homogenization | International |
| International Conference on Harmonization | Medical |
| International Co-operation on Harmonisation | Medical |
| Inter-Cranial Hemorrhage | Medical |
| International Conference of Harmonization | Medical |
| International Co-operation on Harmonization | Medical |
| Intra-Cranial Hemorrhage | Medical |
| International Conference on Harmonisation (of Technical Requirements for Registration of Pharmaceuticals for Human Use) | Medical |
| Intracerebral haemorrhage | Medical |
| Improved Cargo Helicopter | Military and Defence |
| Intel Controller Hub | Networking |
| Interchanger | Space Science |
