| Logistics Center Support System | Business |
| Lumpkin County School System | Community |
| Lutheran Church of South Sudan | Community |
| Lee County School System | Community |
| Liberty County School System | Community |
| Lafayette Catholic School System | Community |
| Lawrence County School System | Community |
| LUMS Community Service Society | Community |
| Leicester City Spike Stars | Community |
| Locality and Community Support Service | Community |
| London Central Secondary School | Community |
| Lambton Christian School Society | Community |
| Lake Cowichan Secondary School | Community |
| Life Community Services Society | Community |
| Local Community Stabilization Share | Community |
| Loucouss Corporation Software and Security | Computing |
| Local Communication Switching System | Computing |
| London Centre for Social Studies | General |
| Lake Calhoun Sailing School | General |
| Land Command Support System | General |
| Longest Common Sub Se | General |
| Longest Common Sub Sequence | General |
| L Cysteine S Sulfate | General |
| Landing Craft Support Small | General |
| Land Combat Support System | General |
| Lycra Circular Short Skirt | General |
| Life Cycle Software Support | Governmental |
| Lightweight Camouflage Screening System | Governmental |
| Lung Cancer Symptom Scale | Medical |
| Laboratory Chemical Safety Summary | Medical |
| Laboratory Chemical Safety Summaries | Medical |
| Lawrence County Social Services | Regional |
