| Society for Computer Applications in Radiology | Academic & Science |
| Scientific Committee on Antarctic Research | Academic & Science |
| Smoke, Clouds, And Radiation | Academic & Science |
| Scientific Committee for Antarctic Research | Academic & Science |
| Standing Committee on Agricultural Research | Academic & Science |
| Shape-Constrained Additive Regression | Academic & Science |
| Supplier Corrective Action Request | Business |
| Spokane Community Against Racism | Community |
| Skibbereen Charity Adventure Race | Community |
| So Crazy About Retrieving | Computing |
| Velhalla | Cryptocurrency |
| Scar Token | Cryptocurrency |
| Situation Challenge Action Result | General |
| Southern Campaigns of the American Revolution | General |
| Sub-Caliber Aircraft Rocket | General |
| Super Car | General |
| Sand Car | General |
| Safety Car | General |
| Stock Car Auto Racing | General |
| Schedario Centrale Auto Rubate | General |
| Standard Car | General |
| Societe Centrafricaine d'Automobile et de Representation | General |
| Small Claim Assessment Review | General |
| Sewer Capacity Availability Review | General |
| Sage Conifer Aspen Riparian | General |
| Serving Christ Applying Rhythm | General |
| Student Coalition For Animal Rights | General |
| South Coast Alternative Radio | General |
| Steel City Autoduel Rampage | General |
| Sulfates Clouds And Radiation | General |
| Springfield Child Abuse Resources | General |
| Small Claims Assessment Review | General |
| Squadra Corse Alfa Romeo | General |
| Special Forces Combat Assault Rifle | Governmental |
| SOF Combat Assault Rifle | Governmental |
| Special Operations Forces Combat Assault Rifle | Governmental |
| Supplemental Court of Appeals Administrative Rule | Governmental |
| Special Combat Aggressive Reactionary | Governmental |
| Survivors Of Childhood Assault And Rape | Governmental |
| Strike Coordination And Reconnaissance | Governmental |
| Save Cure And Rehabilitate | Medical |
| Surviving Cancer Absolute Reality | Medical |
| Arica-Chacalluta, Chile | Regional |
| South Coast Adventure Race | Sports |
| Ski Climb And Ride | Sports |
| Sports Conditioning And Rehab | Sports |
