| SEMester | Academic & Science |
| Space Environment Monitor | Academic & Science |
| Society for Ethnomusicology | Academic & Science |
| Sun, Earth, Moon | Academic & Science |
| Software Engineering Manager | Academic & Science |
| Science, Engineering, and Mathematics | Academic & Science |
| Single European Market | Business |
| General Semiconductor, Inc. | Business |
| Spec Epics Motors | Business |
| Sound and Efficient Management | Business |
| Strategic Enterprise Management | Business |
| Someone Else's Money | Business |
| Search Engine Marketing | Business |
| Strategic Enrollment Management | Business Management |
| Solvent Extractable Material | Chemistry |
| Society for Experimental Mechanics | Community |
| Schoolwide Enrichment Model | Community |
| Systematic Evaluation of Members | Community |
| Special Education and Middle school | Community |
| Sexually Explicit Material | Community |
| Smartstream Encryption Modulator | Computer Hardware |
| Simply Expensive Machine | Computing |
| State Event Machines | Computing |
| Scripture Encoding Model | Computing |
| System Error Message | Computing |
| Server Enterprise Manager | Computing |
| Symantec Event Manager | Computing |
| Scalar Equation Method | Computing |
| Station Emulation Mode | Computing |
| Sql Enterprise Manager | Computing |
| Security Event Management | Computing |
| Semux | Cryptocurrency |
| Synthesizer Expander Module | Electronics |
| Session Experience Manager | General |
| Scanning Electron Microscopy | General |
| Structural Equation Modelling | General |
| Set of Eye Movement | General |
| Sonido En Movimiento | General |
| South East Motor | General |
| Shift Energy Management | General |
| Shell Eco Marathon | General |
| South East Mopars | General |
| Steptoe Edwards Motors | General |
| Square Enix Mobile | General |
| Schoolwide Enrichment Myschoolonline | General |
| Seller's Engineering Memorandum | Governmental |
| SERAM | Indian Railway Station |
| Societe Des Establissements Modernes | International |
| Societe Des Etablissements Modernes | International |
| Search Engine Marketer | Jobs |
| Standard Error of Mean | Maths |
| Structural Equation Modeling | Maths |
| Systolic Ejection Murmur | Medical |
| Semen | Medical |
| Smooth Eye Movements | Medical |
| Scanning Emectron Microscopy | Physics Related |
| Secondary Electron Multiplier | Physics Related |
| Structural Equation Models | Physics Related |
| Standard Error of Measurement | Physics Related |
| Semitic - Other | Regional |
| Southern Europe and Mediterranean | Regional |
| South-East Michigan | Regional |
| Synthesis Enterprise Manager | Softwares |
| Silly Equipment Manager | Softwares |
| Sample Exchange Mechanism | Space Science |
| Scanning Electron Microscope | Space Science |
| Space Environment Monitoring | Space Science |
| Spacecraft Equipment Module | Space Science |
| System Engineering Management | Space Science |
| Sports and Exercise Medicine | Sports |
| Stock Exchange of Mauritius | Stock Exchange |
