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INFO: Full form for JHJ is Juvenon Health Journal in Medical category
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Huntington's disease (HD), also known as Huntington's chorea, is a neurodegenerative disease that is mostly inherited. The earliest symptoms are often subtle problems with mood or mental abilities. A general lack of coordination and an unsteady gait often follow. It is also a basal ganglia disease causing a hyperkinetic movement disorder known as chorea. As the disease advances, uncoordinated, involuntary body movements of chorea become more apparent. Physical abilities gradually worsen until coordinated movement becomes difficult and the person is unable to talk. Mental abilities generally decline into dementia. The specific symptoms vary somewhat between people. Symptoms usually begin between 30 and 50 years of age but can start at any age. The disease may develop earlier in each successive generation. About eight percent of cases start before the age of 20 years, and are known as juvenile HD, which typically present with the slow movement symptoms of Parkinson's disease rather than those of chorea.

HD is typically inherited from an affected parent, who carries a mutation in the huntingtin gene (HTT). However, up to 10% of cases are due to a new mutation. The huntingtin gene provides the genetic information for huntingtin protein (Htt). Expansion of CAG repeats of cytosine-adenine-guanine (known as a trinucleotide repeat expansion) in the gene coding for the huntingtin protein results in an abnormal mutant protein (mHtt), which gradually damages brain cells through a number of possible mechanisms. Diagnosis is by genetic testing, which can be carried out at any time, regardless of whether or not symptoms are present. This fact raises several ethical debates: the age at which an individual is considered mature enough to choose testing; whether parents have the right to have their children tested; and managing confidentiality and disclosure of test results.

No cure for HD is known, and full-time care is required in the later stages. Treatments can relieve some symptoms, and in some, improve quality of life. The best evidence for treatment of the movement problems is with tetrabenazine. HD affects about 4 to 15 in 100,000 people of European descent. It is rare among Japanese, while the occurrence rate in Africa is unknown. The disease affects men and women equally. Complications such as pneumonia, heart disease, and physical injury from falls reduce life expectancy. Suicide is the cause of death in about 9% of cases. Death typically occurs 15–20 years from when the disease was first detected.

The earliest known description of the disease was in 1841 by American physician Charles Oscar Waters. The condition was described in further detail in 1872 by American physician George Huntington. The genetic basis was discovered in 1993 by an international collaborative effort led by the Hereditary Disease Foundation. Research and support organizations began forming in the late 1960s to increase public awareness, provide support for individuals and their families and promote research. Research directions include determining the exact mechanism of the disease, improving animal models to aid with research, testing of medications to treat symptoms or slow the progression of the disease, and studying procedures such as stem-cell therapy with the goal of replacing damaged or lost neurons.

INFO: Full form for IQG is Instituto Qualisa de Gestão (in Portuguese) Qualisa Institute of Management in Medical category
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INFO: Full form for IKD is Indoor Kid Disorder in Medical category
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The Johns Hopkins Hospital (JHH) is the teaching hospital and biomedical research facility of the Johns Hopkins School of Medicine, located in Baltimore, Maryland, U.S. It was founded in 1889 using money from a bequest of over $7 million (1873 money, worth 134.7 million dollars in 2016) by city merchant, banker/financier, civic leader and philanthropist Johns Hopkins (1795–1873). Johns Hopkins Hospital and its school of medicine are considered to be the founding institutions of modern American medicine and the birthplace of numerous famous medical traditions including rounds, residents and house staff. Many medical specialties were formed at the hospital including neurosurgery, by Harvey Cushing and Walter Dandy; cardiac surgery by Alfred Blalock; and child psychiatry, by Leo Kanner. Attached to the hospital is the Johns Hopkins Children’s Center which serves infants, children, teens, and young adults aged 0–21.

Johns Hopkins Hospital is widely regarded as one of the world's greatest hospitals and medical institutions. It was ranked by U.S. News & World Report news magazine as the best overall hospital in America for 21 consecutive years (1991–2011). In 2019–2020, U.S. News & World Report ranked the hospital on 15 adult specialties and 10 children's specialties; the hospital came in 1st in Maryland and 3rd nationally behind the Mayo Clinic in Rochester, Minnesota and Mass General in Boston, Massachusetts.

The New Jewish Home (formerly Jewish Home Lifecare among other prior names) is an American nonprofit older adult health care system based in New York City. The organization serves older adults of all religions and ethnicities at its three campuses in Manhattan, The Bronx, and Mamaroneck in Westchester County. It provides rehabilitative services, skilled nursing, senior housing, and numerous home health programs, including a certified home health agency and a home care agency. The organization was founded in 1848 by Hannah Leo of the B'nai Jeshurun Ladies' Benevolent Society.

INFO: Full form for HSAR is Health Sciences Author Recognition in Medical category
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INFO: Full form for IBHA is Improve Behavioral Healthcare Access in Medical category
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INFO: Full form for PFZ is Porcelain Fused to Zirconia in Medical category
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INFO: Full form for STH is Sheffield Teaching Hospitals in Medical category
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Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. GH also stimulates production of IGF-1 and increases the concentration of glucose and free fatty acids. It is a type of mitogen which is specific only to the receptors on certain types of cells. GH is a 191-amino acid, single-chain polypeptide that is synthesized, stored and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland.

A recombinant form of hGH called somatropin (INN) is used as a prescription drug to treat children's growth disorders and adult growth hormone deficiency. In the United States, it is only available legally from pharmacies by prescription from a licensed health care provider. In recent years in the United States, some health care providers are prescribing growth hormone in the elderly to increase vitality. While legal, the efficacy and safety of this use for HGH has not been tested in a clinical trial. Many of the functions of hGH remain unknown.

In its role as an anabolic agent, HGH has been used by competitors in sports since at least 1982, and has been banned by the IOC and NCAA. Traditional urine analysis does not detect doping with HGH, so the ban was not enforced until the early 2000s, when blood tests that could distinguish between natural and artificial HGH were starting to be developed. Blood tests conducted by WADA at the 2004 Olympic Games in Athens, Greece targeted primarily HGH. Use of the drug for performance enhancement is not currently approved by the FDA.

GH has been studied for use in raising livestock more efficiently in industrial agriculture and several efforts have been made to obtain governmental approval to use GH in livestock production. These uses have been controversial. In the United States, the only FDA-approved use of GH for livestock is the use of a cow-specific form of GH called bovine somatotropin for increasing milk production in dairy cows. Retailers are permitted to label containers of milk as produced with or without bovine somatotropin.

INFO: Full form for STH is Sheffield Teaching Hospital in Medical category
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INFO: Full form for SHT is Short Histidine Tag in Medical category
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INFO: Full form for SHT is Severe Head Trauma in Medical category
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INFO: Full form for SHT is Systemic HyperTension in Medical category
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INFO: Full form for RAK is Right Above Knee amputation in Medical category
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Columbidae () is a bird family consisting of pigeons and doves. It is the only family in the order Columbiformes. These are stout-bodied birds with short necks, and short slender bills that in some species feature fleshy ceres. They primarily feed on seeds, fruits, and plants. The family occurs worldwide, but the greatest variety is in the Indomalayan and Australasian realms.

The family contains 344 species divided into 50 genera. Thirteen of the species are extinct.

In English, the smaller species tend to be called "doves" and the larger ones "pigeons". However, the distinction is not consistent, and does not exist in most other languages. Historically, the common names for these birds involve a great deal of variation between the terms. The bird most commonly referred to as just "pigeon" is the domestic pigeon, which is common in many cities as the feral pigeon.

Pigeon is a French word that derives from the Latin pipio, for a "peeping" chick, while dove is an ultimately Germanic word that refers to the bird's diving flight. The English dialectal word culver appears to derive from Latin columba. A group of doves is called a "dule", taken from the French word deuil ('mourning').

Doves and pigeons build relatively flimsy nests, often using sticks and other debris, which may be placed on branches of trees, on ledges, or on the ground, depending on species. They lay one or (usually) two white eggs at a time, and both parents care for the young, which leave the nest after 25–32 days. Unfledged baby doves and pigeons are called squabs and are generally able to fly by 5 weeks of age. These fledglings, with their immature squeaking voices, are called squeakers once they are weaned or weaning. Unlike most birds, both sexes of doves and pigeons produce "crop milk" to feed to their young, secreted by a sloughing of fluid-filled cells from the lining of the crop.

INFO: Full form for PDJ is Parkinson Disease and Juvenile in Medical category
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INFO: Full form for PDJ is Parkinson Disease Juvenile in Medical category
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Before I Wake may refer to:

INFO: Full form for TKO is To Keep Open in Medical category
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The Gynecologic Oncology Group (GOG) is a non-profit organization funded by the National Cancer Institute with the purpose of supporting research for the prevention and treatment of all gynecologic cancers, such as ovarian cancer, cervical cancer, endometrial cancer, vulvar cancer, and vaginal cancer.

The GOG was founded in 1970 by a group of gynecologic surgeons from 11 institutions. The formation of the GOG was the result of the recognition of the need for collaborative research in the gynecologic malignancies. Before the GOG was founded, most clinical trials were small studies from single institutions or case reports and lacked the statistical power to convince physicians around the world to adopt innovative treatment strategies. The GOG has now grown to include over 50 research centers and has over 160 affiliated institutions. Its members make up a multi-disciplinary group, consisting of gynecologic oncologists, medical oncologists, pathologists, radiation oncologists, nurses, statisticians, and basic scientists.

Over 3,000 patients are treated each year on GOG protocols. As of 2004, the GOG has completed over 300 trials and published over 550 papers.

INFO: Full form for GOA is Geldings Of America in Medical category
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Gulf War syndrome or Gulf War illness is a chronic and multi-symptomatic disorder affecting returning military veterans of the 1990–1991 Persian Gulf War. A wide range of acute and chronic symptoms have been linked to it, including fatigue, muscle pain, cognitive problems, insomnia, rashes and diarrhea. Approximately 250,000 of the 697,000 U.S. veterans who served in the 1991 Gulf War are afflicted with enduring chronic multi-symptom illness, a condition with serious consequences.

The Royal British Legion said research suggested up to 33,000 UK Gulf War veterans could be living with the syndrome, with 1,300 claiming a war pension for conditions connected to their service. In 2007 the Royal British Legion produced a comprehensive report entitled Legacy of Suspicion, which made recommendations about necessary research and compensation. The Royal British Legion is still campaigning for the UK government to properly address the suffering of veterans of the Gulf War.

From 1995 to 2005, the health of combat veterans worsened in comparison with nondeployed veterans, with the onset of more new chronic diseases, functional impairment, repeated clinic visits and hospitalizations, chronic fatigue syndrome-like illness, posttraumatic stress disorder, and greater persistence of adverse health incidents.

Exposure to pesticides and exposure to pills containing pyridostigmine bromide (used as a pretreatment to protect against nerve agent effects) has been found to be associated with the neurological effects seen in Gulf war syndrome. Other causes that have been investigated are sarin, cyclosarin, and emissions from oil well fires, but their relationship to the illness is not as clear.

Studies have consistently indicated that Gulf War syndrome is not the result of combat or other stressors and that Gulf War veterans have lower rates of posttraumatic stress disorder (PTSD) than veterans of other wars.

According to a 2013 report by the Iraq and Afghanistan Veterans of America, veterans of the U.S. wars in Iraq and Afghanistan may also suffer from Gulf War syndrome, though later findings identified causes that would not have been present in those wars.

Hemoglobin or haemoglobin (spelling differences) (from the Greek word αἷμα, haîma 'blood' + Latin globus 'ball, sphere' + -in) (), abbreviated Hb or Hgb, is the iron-containing oxygen-transport metalloprotein in the red blood cells (erythrocytes) of almost all vertebrates (the exception being the fish family Channichthyidae) as well as the tissues of some invertebrates. Hemoglobin in blood carries oxygen from the lungs or gills to the rest of the body (i.e. the tissues). There it releases the oxygen to permit aerobic respiration to provide energy to power the functions of the organism in the process called metabolism. A healthy individual has 12 to 20 grams of hemoglobin in every 100 mL of blood.

In mammals, the protein makes up about 96% of the red blood cells' dry content (by weight), and around 35% of the total content (including water). Hemoglobin has an oxygen-binding capacity of 1.34 mL O2 per gram, which increases the total blood oxygen capacity seventy-fold compared to dissolved oxygen in blood. The mammalian hemoglobin molecule can bind (carry) up to four oxygen molecules.

Hemoglobin is involved in the transport of other gases: It carries some of the body's respiratory carbon dioxide (about 20–25% of the total) as carbaminohemoglobin, in which CO2 is bound to the heme protein. The molecule also carries the important regulatory molecule nitric oxide bound to a globin protein thiol group, releasing it at the same time as oxygen.

Hemoglobin is also found outside red blood cells and their progenitor lines. Other cells that contain hemoglobin include the A9 dopaminergic neurons in the substantia nigra, macrophages, alveolar cells, lungs, retinal pigment epithelium, hepatocytes, mesangial cells in the kidney, endometrial cells, cervical cells and vaginal epithelial cells. In these tissues, hemoglobin has a non-oxygen-carrying function as an antioxidant and a regulator of iron metabolism. Excessive glucose in one's blood can attach to hemoglobin and raise the level of hemoglobin A1c.

Hemoglobin and hemoglobin-like molecules are also found in many invertebrates, fungi, and plants. In these organisms, hemoglobins may carry oxygen, or they may act to transport and regulate other small molecules and ions such as carbon dioxide, nitric oxide, hydrogen sulfide and sulfide. A variant of the molecule, called leghemoglobin, is used to scavenge oxygen away from anaerobic systems, such as the nitrogen-fixing nodules of leguminous plants, lest the oxygen poison (deactivate) the system.

Hemoglobinemia is a medical condition in which there is an excess of hemoglobin in the blood plasma. This is an effect of intravascular hemolysis, in which hemoglobin separates from red blood cells, a form of anemia.

Humans (Homo sapiens) are the most abundant and widespread species of primate, characterized by bipedalism, large and complex brains enabling the development of advanced tools, culture, and language. Humans are highly social beings and tend to live in complex social structures composed of many cooperating and competing groups, from families and kinship networks to political states. Social interactions between humans have established a wide variety of values, social norms, and rituals, which bolster human society. Curiosity and the human desire to understand and influence the environment and to explain and manipulate phenomena have motivated humanity's development of science, philosophy, mythology, religion, and other fields of knowledge.

Although some scientists equate humans with all members of the genus Homo, in common usage it generally refers to Homo sapiens, the only extant member. H. sapiens emerged around 300,000 years ago, evolving from Homo heidelbergensis and migrating out of Africa, gradually replacing local populations of archaic humans. For most of history, all humans were nomadic hunter-gatherers. The Neolithic Revolution, which began in Southwest Asia around 13,000 years ago, saw the emergence of agriculture and permanent human settlement. As populations became larger and denser, forms of governance developed within and between communities and a number of civilizations have risen and fallen. Humans have continued to expand, with a global population of over 7.9 billion in July 2021.

Genes and the environment influence human biological variation in visible characteristics, physiology, disease susceptibility, mental abilities, body size and life span. Though humans vary in many traits (such as genetic predispositions and physical features), two humans on average are over 99% similar, with the most genetically diverse populations from Africa.

Humans are sexually dimorphic. At puberty, humans develop secondary sex characteristics. Women are capable of pregnancy, and undergo menopause and become infertile at around the age of 50. The nature of male and female gender roles has varied historically, and challenges to predominant gender norms have recurred in many societies.

Humans are omnivorous, capable of consuming a wide variety of plant and animal material, and have used fire and other forms of heat to prepare and cook food since the time of H. erectus. They can survive for up to eight weeks without food, and three or four days without water. Humans are generally diurnal, sleeping on average seven to nine hours per day. Childbirth is dangerous, with a high risk of complications and death. Often, both the mother and the father provide care for their children, who are helpless at birth.

Humans have a large and highly developed prefrontal cortex, the region of the brain associated with higher cognition. They are intelligent beings, capable of episodic memory, flexible facial expressions, self-awareness and a theory of mind. The human mind is capable of introspection, private thought, imagination, volition and forming views on existence. This has allowed great technological advancements and complex tool development possible through reason and the transmission of knowledge to future generations. Language, art and trade are defining characteristics of humans. Long-distance trade routes might have led to cultural explosions and resource distribution that gave humans an advantage over other similar species.

The human brain is the central organ of the human nervous system, and with the spinal cord makes up the central nervous system. The brain consists of the cerebrum, the brainstem and the cerebellum. It controls most of the activities of the body, processing, integrating, and coordinating the information it receives from the sense organs, and making decisions as to the instructions sent to the rest of the body. The brain is contained in, and protected by, the skull bones of the head.

The cerebrum, the largest part of the human brain, consists of two cerebral hemispheres. Each hemisphere has an inner core composed of white matter, and an outer surface – the cerebral cortex – composed of grey matter. The cortex has an outer layer, the neocortex, and an inner allocortex. The neocortex is made up of six neuronal layers, while the allocortex has three or four. Each hemisphere is conventionally divided into four lobes – the frontal, temporal, parietal, and occipital lobes. The frontal lobe is associated with executive functions including self-control, planning, reasoning, and abstract thought, while the occipital lobe is dedicated to vision. Within each lobe, cortical areas are associated with specific functions, such as the sensory, motor and association regions. Although the left and right hemispheres are broadly similar in shape and function, some functions are associated with one side, such as language in the left and visual-spatial ability in the right. The hemispheres are connected by commissural nerve tracts, the largest being the corpus callosum.

The cerebrum is connected by the brainstem to the spinal cord. The brainstem consists of the midbrain, the pons, and the medulla oblongata. The cerebellum is connected to the brainstem by three pairs of nerve tracts called cerebellar peduncles. Within the cerebrum is the ventricular system, consisting of four interconnected ventricles in which cerebrospinal fluid is produced and circulated. Underneath the cerebral cortex are several important structures, including the thalamus, the epithalamus, the pineal gland, the hypothalamus, the pituitary gland, and the subthalamus; the limbic structures, including the amygdala and the hippocampus; the claustrum, the various nuclei of the basal ganglia; the basal forebrain structures, and the three circumventricular organs. The cells of the brain include neurons and supportive glial cells. There are more than 86 billion neurons in the brain, and a more or less equal number of other cells. Brain activity is made possible by the interconnections of neurons and their release of neurotransmitters in response to nerve impulses. Neurons connect to form neural pathways, neural circuits, and elaborate network systems. The whole circuitry is driven by the process of neurotransmission.

The brain is protected by the skull, suspended in cerebrospinal fluid, and isolated from the bloodstream by the blood–brain barrier. However, the brain is still susceptible to damage, disease, and infection. Damage can be caused by trauma, or a loss of blood supply known as a stroke. The brain is susceptible to degenerative disorders, such as Parkinson's disease, dementias including Alzheimer's disease, and multiple sclerosis. Psychiatric conditions, including schizophrenia and clinical depression, are thought to be associated with brain dysfunctions. The brain can also be the site of tumours, both benign and malignant; these mostly originate from other sites in the body.

The study of the anatomy of the brain is neuroanatomy, while the study of its function is neuroscience. Numerous techniques are used to study the brain. Specimens from other animals, which may be examined microscopically, have traditionally provided much information. Medical imaging technologies such as functional neuroimaging, and electroencephalography (EEG) recordings are important in studying the brain. The medical history of people with brain injury has provided insight into the function of each part of the brain. Brain research has evolved over time, with philosophical, experimental, and theoretical phases. An emerging phase may be to simulate brain activity.

In culture, the philosophy of mind has for centuries attempted to address the question of the nature of consciousness and the mind-body problem. The pseudoscience of phrenology attempted to localise personality attributes to regions of the cortex in the 19th century. In science fiction, brain transplants are imagined in tales such as the 1942 Donovan's Brain.

Half-Breed may refer to:

Heartbeat or heartbeats may refer to:

INFO: Full form for HB is Half Blind in Medical category
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