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MedStar Franklin Square Medical Center, a member of MedStar Health, is a hospital located in the Rosedale area of eastern Baltimore County, Maryland. It is the third largest hospital in Maryland; with more than 3,500 employees, it is one of the largest employers in Baltimore County.

The building is found along Franklin Square Drive, next to the campus of Community College of Baltimore County - Essex, and is used for the clinical training of allied health programs at the college.

INFO: Full form for FSH is Follicle-stimulating Hormone in Medical category
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INFO: Full form for FSH is FacioScapuloHumeral Muscular Dystrophy Society in Medical category
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INFO: Full form for FSH is Front Stuff Hormone in Medical category
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Facioscapulohumeral muscular dystrophy (FSHD) is a type of muscular dystrophy, a group of heritable diseases that cause progressive impairment of muscles. FSHD preferentially weakens the skeletal muscles of the face (Latin: facio), those that position the scapula (scapulo), and those in the upper arm, overlying the humerus bone (humeral). These areas can be spared, and others usually are affected, especially the chest, the trunk, and around the shin. Abnormally positioned scapulas (winged scapulas) and inability to lift the foot (foot drop) are common. The two sides of the body are often affected unequally. Weakness typically manifests at ages 15 – 30 years. FSHD can also cause hearing loss and blood vessel abnormalities in the back of the eye.

FSHD is caused by a genetic mutation leading to deregulation of the DUX4 gene. Normally, DUX4 is expressed (i.e., turned on) in cells of the ovary and in very early human development, becoming repressed (i.e., turned off) by the time an embryo is several days old. In FSHD, DUX4 is inadequately repressed, allowing sporadic expression throughout life. Deletion of DNA in the region surrounding DUX4 is the causative mutation in 95% of cases, termed "D4Z4 contraction" and defining FSHD type 1 (FSHD1). FSHD caused by other mutations is FSHD type 2 (FSHD2). For disease to develop, also required is a 4qA allele, which is a common variation in the DNA next to DUX4. The chances of a D4Z4 contraction with a 4qA allele being passed on to a child is 50% (autosomal dominant); in 30% of cases, the mutation arose spontaneously. Mutations of FSHD cause inadequate DUX4 repression by unpacking the DNA around DUX4, making it accessible to be copied into messenger RNA (mRNA). The 4qA allele stabilizes this DUX4 mRNA, allowing it to be used for production of DUX4 protein. DUX4 protein is a modulator of hundreds of other genes, many of which are involved in muscle function. How this genetic modulation causes muscle damage remains unclear.

Signs, symptoms, family history, and diagnostic tests can suggest FSHD; genetic testing provides definitive diagnosis. No intervention has proven effective for slowing progression of weakness. Screening allows for early detection and intervention for various disease complications. Symptoms can be addressed with physical therapy, bracing, and reconstructive surgery such as surgical fixation of the scapula to the thorax. FSHD affects up to 1 in 8,333 people, putting it in the three most common muscular dystrophies with myotonic dystrophy and Duchenne muscular dystrophy. Prognosis is variable. Many are not significantly limited in daily activity, whereas a wheel chair or scooter is required in 20% of cases. Life expectancy is generally not affected, except in rare cases of respiratory insufficiency.

FSHD was first distinguished as a disease in the 1870s and 1880s when French physicians Louis Théophile Joseph Landouzy and Joseph Jules Dejerine followed a family affected by it, thus the initial name Landouzy–Dejerine muscular dystrophy. Their work is predated by descriptions of probable individual FSHD cases. The significance of D4Z4 contraction on chromosome 4 was established in the 1990s. The DUX4 gene was discovered in 1999, found to be expressed and toxic in 2007, and in 2010 the genetic mechanism causing its expression was elucidated. In 2012, the gene most frequently mutated in FSHD2 was identified. In 2019, the first drug designed to counteract DUX4 expression entered clinical trials.

INFO: Full form for IDMA is Indian Drugs Manufacturers Association in Medical category
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INFO: Full form for FSGO is Florida Society of Gynecologic Oncology in Medical category
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Focal segmental glomerulosclerosis (FSGS), also known as “focal glomerular sclerosis” or “focal nodular glomerulosclerosis,” is a histopathologic finding of scarring (sclerosis) of glomeruli and damage to renal podocytes. This process damages the filtration function of the kidney, resulting in protein loss in the urine. FSGS is a leading cause of excess protein loss--nephrotic syndrome—in children and adults. Signs and symptoms include proteinuria, water retention, and edema. Kidney failure is a common long-term complication of disease. FSGS can be classified as primary versus secondary depending on whether a particular toxic or pathologic stressor can be identified as the cause. Diagnosis is established by renal biopsy, and treatment consists of glucocorticoids and other immune-modulatory drugs. Response to therapy is variable, with a significant portion of patients progressing to end-stage kidney failure. FSGS is estimated to occur in 2-3 persons per million, with males and African peoples at higher risk .

Focal segmental glomerulosclerosis (FSGS), also known as “focal glomerular sclerosis” or “focal nodular glomerulosclerosis,” is a histopathologic finding of scarring (sclerosis) of glomeruli and damage to renal podocytes. This process damages the filtration function of the kidney, resulting in protein loss in the urine. FSGS is a leading cause of excess protein loss--nephrotic syndrome—in children and adults. Signs and symptoms include proteinuria, water retention, and edema. Kidney failure is a common long-term complication of disease. FSGS can be classified as primary versus secondary depending on whether a particular toxic or pathologic stressor can be identified as the cause. Diagnosis is established by renal biopsy, and treatment consists of glucocorticoids and other immune-modulatory drugs. Response to therapy is variable, with a significant portion of patients progressing to end-stage kidney failure. FSGS is estimated to occur in 2-3 persons per million, with males and African peoples at higher risk .

INFO: Full form for ATOM is Accelerating Therapeutics for Opportunities in Medicine in Medical category
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INFO: Full form for PDIC is Pig Disease Information Centre in Medical category
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INFO: Full form for MCCP is Maine Children's Cancer Program in Medical category
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INFO: Full form for MCCP is Medical Claims Conciliation Panel in Medical category
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INFO: Full form for MCCP is Medical Care for Children Partnership in Medical category
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INFO: Full form for AIED is Autoimmune Inner Ear Disease in Medical category
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INFO: Full form for PDIC is Parkinsons Disease Implementation Committee in Medical category
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INFO: Full form for PDIC is Poison and Drug Information Center in Medical category
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INFO: Full form for PDIC is Plant Disease and Insect Clinic in Medical category
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INFO: Full form for PDIC is Poison Drug Information Center in Medical category
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INFO: Full form for PDIC is Pediatric Device Innovation Consortium in Medical category
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INFO: Full form for MTMS is Medication Therapy Management Services in Medical category
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INFO: Full form for MTMS is Medication Therapy Management Service in Medical category
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INFO: Full form for SEPS is Subfascial Endoscopic Perforator Surgery in Medical category
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INFO: Full form for SOPE is Society of Pediatric Echocardiography in Medical category
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INFO: Full form for SPRC is Stevens Pharmaceutical Research Center in Medical category
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INFO: Full form for PSDL is Primary Standards Dosimetry Laboratory in Medical category
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INFO: Full form for PSDL is Precision Systems Design Laboratory in Medical category
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INFO: Full form for PSDL is Primary standards dosimetry laboratories in Medical category
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INFO: Full form for SWHP is Scott White Health Plan in Medical category
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INFO: Full form for SWHP is Sactwu Worker Health Program in Medical category
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INFO: Full form for SWHP is SACTWU Worker Health Programme in Medical category
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INFO: Full form for SWH is South West Healthcare in Medical category
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INFO: Full form for SWH is Senior Whole Health in Medical category
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INFO: Full form for ESDS is Educational Support and Disability Services in Medical category
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INFO: Full form for PENS is Percutaneous Electrical Nerve Stimulation in Medical category
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INFO: Full form for PENS is Patterned Electrical Neuromuscular Stimulation in Medical category
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INFO: Full form for CTPP is Chicago Tobacco Prevention Project in Medical category
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INFO: Full form for SSRT is Spiritual Self Reevaluation Therapy in Medical category
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INFO: Full form for SSRT is Stereotactic Synchrotron Radiation Therapy in Medical category
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INFO: Full form for SSRT is Sympathetic Skin Response Test in Medical category
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INFO: Full form for MCCR is Medical Care Cost Recovery in Medical category
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INFO: Full form for MCCR is Methods in Clinical Cancer Research in Medical category
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INFO: Full form for MCCR is Medical Committee for Civil Rights in Medical category
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INFO: Full form for MCCR is Manipal Centre for Clinical Research in Medical category
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INFO: Full form for MCCR is Mediterranean Center for Cancer Research in Medical category
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INFO: Full form for MCCR is Molecular and Clinical Cancer Research in Medical category
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INFO: Full form for MCCR is Monaro Committee for Cancer Research in Medical category
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INFO: Full form for MCCR is Medical Center for Clinical Research in Medical category
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INFO: Full form for IAOP is International Autism Outreach Project in Medical category
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