Explore topic-wise fullforms in Medical

INFO: Full form for TGLP is Tuberculosis Genotyping Laboratory Procedures in Medical category
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INFO: Full form for WDF is Warm, Dry and Fleshtoned in Medical category
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INFO: Full form for WDES is Workforce Disability Equality Standard in Medical category
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INFO: Full form for WNL is White Neutrophil Lymphocyte in Medical category
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INFO: Full form for DTQ is Disease Threat Questionnaire in Medical category
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INFO: Full form for WOSH is Wildwood Orthopaedic and Spine Hospital in Medical category
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INFO: Full form for WOSH is Worker Occupational Safety Health in Medical category
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INFO: Full form for WOSH is Western Occupational Safety and Health Group in Medical category
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INFO: Full form for WOSH is Worker Occupational Safety and Health in Medical category
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INFO: Full form for WDPT is Wallerian Degeneration of the Pyramidal Tract in Medical category
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INFO: Full form for AWF is Animal Welfare Foundation (of the BVA) in Medical category
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INFO: Full form for HTGI is Human Tumor Gene Index in Medical category
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INFO: Full form for MLME is Mobile Laboratory of Measuring Equipment in Medical category
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INFO: Full form for NFN is National Federation of Nurses in Medical category
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Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from a somatic cell. The iPSC technology was pioneered by Shinya Yamanaka’s lab in Kyoto, Japan, who showed in 2006 that the introduction of four specific genes (named Myc, Oct3/4, Sox2 and Klf4), collectively known as Yamanaka factors, encoding transcription factors could convert somatic cells into pluripotent stem cells. He was awarded the 2012 Nobel Prize along with Sir John Gurdon "for the discovery that mature cells can be reprogrammed to become pluripotent."

Pluripotent stem cells hold promise in the field of regenerative medicine. Because they can propagate indefinitely, as well as give rise to every other cell type in the body (such as neurons, heart, pancreatic, and liver cells), they represent a single source of cells that could be used to replace those lost to damage or disease.

The most well-known type of pluripotent stem cell is the embryonic stem cell. However, since the generation of embryonic stem cells involves destruction (or at least manipulation) of the pre-implantation stage embryo, there has been much controversy surrounding their use. Patient-matched embryonic stem cell lines can now be derived using somatic cell nuclear transfer (SCNT).

Since iPSCs can be derived directly from adult tissues, they not only bypass the need for embryos, but can be made in a patient-matched manner, which means that each individual could have their own pluripotent stem cell line. These unlimited supplies of autologous cells could be used to generate transplants without the risk of immune rejection. While the iPSC technology has not yet advanced to a stage where therapeutic transplants have been deemed safe, iPSCs are readily being used in personalized drug discovery efforts and understanding the patient-specific basis of disease.

Yamanaka named iPSCs with a lower case "i" due to the popularity of the iPod and other products.

In his Nobel seminar, Yamanaka cited the earlier seminal work of Harold Weintraub on the role of MyoD in reprogramming cell fate to a muscle lineage as an important precursor to the discovery of IPSCs.

INFO: Full form for ILMV is Inactivated L. Monocytogenes Vaccine in Medical category
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INFO: Full form for GPDT is Genetic Predisposition DNA Testing in Medical category
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INFO: Full form for IOFB is Intraocular foreign body in Medical category
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INFO: Full form for TRBL is Temporary Revenue Borrowing Limit (part of capital control framework) in Medical category
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INFO: Full form for TRBL is Temporary Revenue-Borrowing Limit in Medical category
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INFO: Full form for STSH is Sensitive Thyroid Stimulating Hormone in Medical category
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INFO: Full form for PODH is patient's own drugs at home in Medical category
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INFO: Full form for WOH is World Of Hurt in Medical category
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INFO: Full form for RRLW is Reduce Risk Live Well in Medical category
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INFO: Full form for HOPA is Horizontal Open Probing Attachment in Medical category
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INFO: Full form for HOPA is Hematology/Oncology Pharmacy Association in Medical category
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INFO: Full form for WGH is Warren General Hospital in Medical category
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INFO: Full form for WGH is Whidbey General Hospital in Medical category
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INFO: Full form for WGH is Wahiawa General Hospital in Medical category
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The Western General Hospital (often abbreviated to simply ‘The Western General’) is a health facility at Crewe Road, Edinburgh, Scotland. It is managed by NHS Lothian.

INFO: Full form for WGH is Wayne General Hospital in Medical category
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INFO: Full form for DIRM is Delaware Institute for Reproductive Medicine in Medical category
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INFO: Full form for IDCF is ImmunoDiffusion Complement Fixation in Medical category
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INFO: Full form for CMSN is Children's Medical Services Network in Medical category
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INFO: Full form for INRT is Involved-Node RadioTherapy in Medical category
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INFO: Full form for INRT is Involved Nodal Radiation Therapy in Medical category
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INFO: Full form for INRT is Intranasal Reflex Therapy (INRT): A Method For Reducing Headache Symptoms In Chronic Sinusitis in Medical category
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INFO: Full form for INRT is Involved Node Radiation Therapy in Medical category
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INFO: Full form for HMOT is Home Medical Oxygen Therapy in Medical category
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INFO: Full form for DBH is Doctorate of Behavioral Health in Medical category
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INFO: Full form for DBH is Division of Behavioral Health in Medical category
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INFO: Full form for DBH is Department of Behavioral Health's in Medical category
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INFO: Full form for DBH is Davis Behavioral Health in Medical category
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INFO: Full form for TWG is Total Weight Gain in Medical category
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INFO: Full form for PFI is Personal Finance Index in Medical category
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INFO: Full form for PFI is Portal Flow Index in Medical category
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INFO: Full form for PFI is Pulsatile Flow Index in Medical category
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INFO: Full form for PFI is Progression-Free Interval in Medical category
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INFO: Full form for PFI is Profits From Illness in Medical category
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INFO: Full form for WHF is Wisconsin Health Fund in Medical category
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